Dose-Ranging Efficacy and Safety Study of Albuterol Multidose Dry Powder Inhaler (MDPI) vs Albuterol Hydrofluoroalkane (HFA) and Placebo MDPI in Children With Asthma
نویسندگان
چکیده
منابع مشابه
Twelve- and 52-week safety of albuterol multidose dry powder inhaler in patients with persistent asthma.
OBJECTIVE Evaluate the safety of albuterol multidose dry powder inhaler (MDPI), a novel, inhalation-driven device that does not require coordination of actuation with inhalation, in patients with persistent asthma. METHODS We report pooled safety data from two 12-week, multicenter, randomized, double-blind, repeat-dose, parallel-group studies and the 12-week double-blind phase of a 52-week mu...
متن کاملRelievers, controllers, and inhaler technique: A physician-patient challenge
P hysicians and patients often have different views and perspectives of what constitutes well-controlled asthma. Although patients are routinely informed about the use of inhalers for treatment of their asthma, physicians sometimes overestimate the pa-tient's competence and knowledge of optimal inhaler usage. True to the publication of diverse issues that comprise and challenge the field of all...
متن کاملComparison of albuterol delivered by a metered dose inhaler with spacer versus a nebulizer in children with mild acute asthma.
OBJECTIVE In children with mild acute asthma, to compare treatment with a single dose of albuterol delivered by a metered dose inhaler (MDI) with a spacer in either a weight-adjusted high dose or a standard low-dose regimen with delivery by a nebulizer. STUDY DESIGN In this randomized double-blind trial set in an emergency department, 90 children between 5 and 17 years of age with a baseline ...
متن کاملA comparison of albuterol administered by metered-dose inhaler and spacer with albuterol by nebulizer in adults presenting to an urban emergency department with acute asthma.
STUDY OBJECTIVES To determine the efficacy of albuterol by metered-dose inhaler (MDI) and spacer compared to a nebulizer. DESIGN A prospective, open-label study. SETTING Large urban emergency department (ED). PATIENTS All consecutive adult asthma patients over a 2.5-year period. INTERVENTIONS ED personnel used a standardized treatment algorithm, which included albuterol administered by ...
متن کاملEfficacy of atropine methylnitrate alone and in combination with albuterol in children with asthma.
The bronchodilator effect of nebulized AMN, albuterol and their combination was evaluated in 16 steroid-dependent asthmatic children. In phase 1, maximal bronchodilation was determined by dose-response studies on separate days. Maximal bronchodilator dose of each drug was administered either alone or in combination during phase 2. In phase 1, 0.11 +/- 0.01 mg/kg of albuterol and 0.03 mg/kg of A...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Allergy and Clinical Immunology
سال: 2016
ISSN: 0091-6749
DOI: 10.1016/j.jaci.2015.12.1277